Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.43 |
| ▸ | CNR1 | P21554 | 8/20 | 0.43 |
| ▸ | CNR2 | P34972 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567681 | 1.00 | TRPV1 (0.43) | TRPV1CNR1CNR2MEN1KMT2A | |
| SCHEMBL9567689 | 1.00 | TRPV1 (0.43) | TRPV1CNR1CNR2MEN1KMT2A | |
| SCHEMBL9567697 | 0.77 | TRPV1 (0.38) | TRPV1CNR1CNR2CYP3A4CYP2C19 | |
| SCHEMBL9567695 | 0.77 | TRPV1 (0.38) | TRPV1CNR1CNR2CYP3A4CYP2C19 | |
| SCHEMBL9567753 | 0.76 | SPHK1 (0.36) | TRPV1CNR1CNR2MEN1KMT2A | |
| SCHEMBL9567758 | 0.76 | SPHK1 (0.36) | TRPV1CNR1CNR2MEN1KMT2A | |
| SCHEMBL8715890 | 0.75 | FAAH (0.33) | TRPV1MEN1KMT2ASPHK1FAAH | |
| SCHEMBL9247184 | 0.75 | FAAH (0.33) | TRPV1MEN1KMT2ASPHK1FAAH | |
| SCHEMBL9247176 | 0.75 | FAAH (0.33) | TRPV1MEN1KMT2ASPHK1FAAH | |
| SCHEMBL9567708 | 0.74 | EPHX2 (0.36) | TRPV1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524439-A1 | Novel cyclohexane and tetrahydropyran derivatives and antifungal compositions containing these derivatives | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1993-01-27 | — | — | EP | claimed |