Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046164 | 0.80 | PTGIR (0.37) | PRMT5WDR77 | |
| SCHEMBL9568009 | 0.80 | LMNA (0.56) | PRMT5WDR77HTTTRPM8KCNQ2 | |
| SCHEMBL9567986 | 0.79 | UGCG (0.50) | PRMT5WDR77HTTTRPM8ALDH1A1 | |
| SCHEMBL9567989 | 0.79 | PRMT5 (0.60) | PRMT5WDR77HTTTRPM8KCNQ2 | |
| SCHEMBL9046170 | 0.79 | PTGIR (0.44) | — | |
| SCHEMBL9046175 | 0.78 | PTGIR (0.60) | — | |
| SCHEMBL31297148 | 0.78 | CRBN (0.49) | PRMT5WDR77HTTKCNQ2CRBN | |
| SCHEMBL4220276 | 0.78 | CRBN (0.49) | PRMT5WDR77HTTKCNQ2CRBN | |
| SCHEMBL9568047 | 0.77 | TRPV1 (0.44) | ALDH1A1 | |
| SCHEMBL9568169 | 0.76 | PRMT5 (0.52) | PRMT5WDR77HTTPSMB5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |