Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568042 | 1.00 | SMN1; SMN2 (0.32) | SMN1; SMN2CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1403578 | 0.71 | UGT2B17 (0.36) | — | |
| SCHEMBL9568040 | 0.70 | MCL1 (0.35) | HTT | |
| SCHEMBL8858471 | 0.69 | PTGIR (0.54) | — | |
| SCHEMBL8858469 | 0.69 | PTGIR (0.54) | — | |
| SCHEMBL812885 | 0.69 | HPGD (0.31) | — | |
| SCHEMBL10685924 | 0.68 | HTT (0.65) | CYP2D6HTT | |
| SCHEMBL9568154 | 0.67 | CYP19A1 (0.31) | — | |
| SCHEMBL9048489 | 0.67 | ACHE (0.36) | — | |
| SCHEMBL9048492 | 0.66 | PTGIR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |