Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 7/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568081 | 1.00 | PTGIR (0.41) | PTGIRCYP19A1PREPHTR1AHTR1D | |
| SCHEMBL9047616 | 0.84 | PTGIR (0.43) | PTGIRCYP19A1 | |
| SCHEMBL8858492 | 0.83 | PTGIR (0.66) | PTGIR | |
| SCHEMBL8858488 | 0.83 | PTGIR (0.66) | PTGIR | |
| SCHEMBL9567977 | 0.81 | NPY5R (0.40) | PTGIRMTNR1AMTNR1BGHSRNPY5R | |
| SCHEMBL9567980 | 0.81 | NPY5R (0.40) | PTGIRMTNR1AMTNR1BGHSRNPY5R | |
| SCHEMBL9568058 | 0.77 | NPY1R (0.42) | PTGIRCYP19A1PREPHTR1AHTR1D | |
| SCHEMBL9049221 | 0.70 | GAA (0.34) | PTGIR | |
| SCHEMBL9049217 | 0.70 | GAA (0.34) | PTGIR | |
| SCHEMBL8858420 | 0.69 | PTGIR (0.59) | PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |