Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 4/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.42 |
| ▸ | PTGIR | P43119 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 4/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | TPH1 | P17752 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858443 | 0.81 | PTGIR (0.68) | PTGIR | |
| SCHEMBL9048206 | 0.79 | PTGIR (0.48) | PTGIRCYP19A1 | |
| SCHEMBL9568081 | 0.77 | PTGIR (0.41) | NPY1RNPY5RPTGIRHTR1AHTR1D | |
| SCHEMBL9568085 | 0.77 | PTGIR (0.41) | NPY1RNPY5RPTGIRHTR1AHTR1D | |
| SCHEMBL12422869 | 0.74 | ADRA1D (0.58) | NPY1RNPY5RHTR1AHTR1DADRA1D | |
| SCHEMBL30612421 | 0.70 | DGAT1 (0.58) | HTR1ACYP19A1PREPMTNR1AMTNR1B | |
| SCHEMBL7292707 | 0.70 | DGAT1 (0.58) | HTR1ACYP19A1PREPMTNR1AMTNR1B | |
| SCHEMBL7304447 | 0.70 | DGAT1 (0.58) | HTR1ACYP19A1PREPMTNR1AMTNR1B | |
| SCHEMBL3406500 | 0.70 | DGAT1 (0.58) | HTR1ACYP19A1PREPMTNR1AMTNR1B | |
| SCHEMBL9567980 | 0.69 | NPY5R (0.40) | NPY5RPTGIRMTNR1AMTNR1BGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |