Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 5/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568120 | 0.90 | PRSS1 (0.53) | PRSS1PRSS2PRSS3F2ST14 | |
| SCHEMBL9568110 | 0.89 | ITGB3 (0.52) | PRSS1PRSS2PRSS3F2ST14 | |
| SCHEMBL9422701 | 0.89 | ITGB3 (0.52) | PRSS1PRSS2PRSS3F2ST14 | |
| Hydrochloric Acid SCHEMBL9568180 | 0.89 | PRSS1 (0.52) | PRSS1PRSS2PRSS3F2ST14 | |
| Hydrochloric Acid SCHEMBL9568150 | 0.88 | ITGB3 (0.52) | PRSS1PRSS2PRSS3F2ST14 | |
| Hydrochloric Acid SCHEMBL9568112 | 0.88 | ITGB3 (0.52) | PRSS1PRSS2PRSS3F2ST14 | |
| Hydrochloric Acid SCHEMBL9568100 | 0.88 | ITGB3 (0.52) | PRSS1PRSS2PRSS3F2ST14 | |
| SCHEMBL9568115 | 0.88 | SCN1A (0.46) | PRSS1PRSS2PRSS3F2ST14 | |
| SCHEMBL9568098 | 0.88 | PRSS1 (0.45) | PRSS1PRSS2PRSS3F2ST14 | |
| Hydrochloric Acid SCHEMBL9568176 | 0.87 | PRSS1 (0.47) | PRSS1PRSS2PRSS3F2ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |