Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568399 | 0.87 | LMNA (0.43) | LMNAPRKD3PIM1GSK3AGSK3B | |
| SCHEMBL9568383 | 0.87 | LMNA (0.46) | LMNAPRKD3PIM1GSK3AGSK3B | |
| SCHEMBL9568396 | 0.87 | LMNA (0.49) | LMNAPRKD3PIM1GSK3AGSK3B | |
| SCHEMBL9568452 | 0.86 | LMNA (0.44) | LMNAPRKD3PIM1GSK3AGSK3B | |
| SCHEMBL9568300 | 0.84 | LMNA (0.46) | LMNAPRKD3PIM1GSK3AGSK3B | |
| SCHEMBL9568363 | 0.84 | LMNA (0.48) | LMNAPRKD3PIM1GSK3AGSK3B | |
| SCHEMBL9568381 | 0.84 | LMNA (0.49) | LMNAPRKD3PIM1GSK3AGSK3B | |
| SCHEMBL9568404 | 0.83 | LMNA (0.47) | LMNAPRKD3PIM1GSK3AGSK3B | |
| Hydrochloric Acid SCHEMBL9568307 | 0.82 | LMNA (0.47) | LMNAPRKD3PIM1GSK3AGSK3B | |
| SCHEMBL9568332 | 0.82 | LMNA (0.49) | LMNAPRKD3PIM1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551518-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |