Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 3/20 | 0.56 |
| ▸ | ARG2 | P78540 | 2/20 | 0.56 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | ODC1 | P11926 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1097800 | 1.00 | ARG1 (0.56) | ARG1ARG2NOS3NOS1NOS2 | |
| SCHEMBL14689712 | 0.87 | ARG1 (0.62) | ARG1ARG2NOS3NOS1NOS2 | |
| Water SCHEMBL27925668 | 0.84 | ARG1 (0.64) | ARG1ARG2NOS3NOS1NOS2 | |
| SCHEMBL28009580 | 0.84 | ARG1 (0.64) | ARG1ARG2ODC1LMNARAB9A | |
| SCHEMBL16116350 | 0.81 | ARG1 (0.50) | ARG1ARG2NOS3NOS1NOS2 | |
| SCHEMBL2129918 | 0.81 | ARG1 (0.50) | ARG1ARG2NOS3NOS1NOS2 | |
| SCHEMBL12506358 | 0.81 | ARG1 (0.40) | ARG1ARG2NOS3NOS1NOS2 | |
| SCHEMBL9005591 | 0.80 | ARG1 (0.55) | ARG1ARG2NOS3NOS1NOS2 | |
| SCHEMBL28238488 | 0.80 | ODC1 (0.62) | ARG1ARG2ODC1LMNARAB9A | |
| Hydrochloric Acid SCHEMBL27976606 | 0.79 | ARG1 (0.48) | ARG1ARG2NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107205972-A | Substituted N- (2- (amino) -2-oxoethyl) benzamide inhibitors of autotaxin and their preparation and use in the treatment of LPA-dependent or LPA-mediated diseases | X-RX股份有限公司 | 2017-09-26 | — | — | CN | disclosed |
| EP-0534774-A1 | 5,5-Dialkyl hydantoins for promoted acid gas scrubbing processes | EXXON CHEMICAL PATENTS INC. (US) | 1993-03-31 | — | — | EP | disclosed |