Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568385 | 0.92 | LMNA (0.35) | TOP1LMNAPRKD3PIM1GSK3A | |
| SCHEMBL9568353 | 0.91 | TOP1 (0.36) | TOP1LMNAPRKD3PIM1GSK3A | |
| SCHEMBL9568461 | 0.91 | LMNA (0.36) | LMNAPRKD3PIM1GSK3AGSK3B | |
| SCHEMBL9568442 | 0.90 | PRKD3 (0.35) | LMNAPRKD3PIM1GSK3AGSK3B | |
| SCHEMBL9568423 | 0.86 | TOP1 (0.35) | TOP1LMNAPRKD3PIM1GSK3A | |
| SCHEMBL9568382 | 0.85 | LMNA (0.35) | LMNAPRKD3PIM1GSK3AGSK3B | |
| SCHEMBL9568327 | 0.84 | LMNA (0.47) | TOP1LMNAPRKD3PIM1GSK3A | |
| SCHEMBL9568319 | 0.83 | PRKD3 (0.35) | LMNAPRKD3PIM1GSK3AGSK3B | |
| SCHEMBL9568303 | 0.81 | LMNA (0.37) | LMNAPRKD3PIM1GSK3AGSK3B | |
| SCHEMBL9568393 | 0.81 | PRKD3 (0.36) | LMNAPRKD3PIM1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551518-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |