Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HMGCR | P04035 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26316292 | 0.81 | HMGCR (0.36) | CTSAACHEHMGCR | |
| SCHEMBL3902813 | 0.79 | CTSA (0.41) | CTSAACHE | |
| SCHEMBL25370472 | 0.76 | CTSA (0.38) | CTSAACHE | |
| SCHEMBL26379542 | 0.74 | TSHR (0.42) | CTSAACHEHMGCR | |
| SCHEMBL9068827 | 0.72 | CTSA (0.37) | CTSAACHEHMGCR | |
| SCHEMBL4758253 | 0.72 | CTSA (0.37) | CTSAACHEHMGCR | |
| SCHEMBL575230 | 0.72 | CTSA (0.50) | CTSAACHEHMGCR | |
| SCHEMBL29185038 | 0.68 | CTSA (0.33) | CTSAACHEHMGCR | |
| SCHEMBL9472438 | 0.68 | TSHR (0.40) | CTSAACHEHMGCR | |
| SCHEMBL719105 | 0.66 | CTSA (0.43) | CTSAACHEHMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536817-A1 | Azabicyclic compounds as tachykinin antagonists | MERCK SHARP & DOHME LTD. (GB) | 1993-04-14 | — | — | EP | disclosed |