Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HMGCR | P04035 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26379542 | 0.79 | TSHR (0.42) | CTSAACHEHMGCRPOLBKDM4E | |
| SCHEMBL9068827 | 0.77 | CTSA (0.37) | CTSAACHEHMGCRPOLBKDM4E | |
| SCHEMBL575230 | 0.77 | CTSA (0.50) | CTSAACHEHMGCRPOLBKDM4E | |
| SCHEMBL22234352 | 0.76 | CTSA (0.40) | CTSAACHEPOLBKDM4EALDH1A1 | |
| SCHEMBL29185038 | 0.72 | CTSA (0.33) | CTSAACHEHMGCR | |
| SCHEMBL9568403 | 0.72 | CTSA (0.38) | CTSAACHEHMGCR | |
| SCHEMBL10896423 | 0.71 | GAA (0.31) | GAAATM | |
| SCHEMBL719105 | 0.70 | CTSA (0.43) | CTSAACHEHMGCRPOLBKDM4E | |
| SCHEMBL28846287 | 0.70 | LPAR3 (0.50) | — | |
| SCHEMBL26316292 | 0.70 | HMGCR (0.36) | CTSAACHEHMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212196-B2 | Hypophosphorous acid derivatives having antihyperalgic activity and biological applications thereof | UNIVERSITE PARIS DESCARTES (FR) | 2015-12-15 | — | — | US | disclosed |
| US-20140107078-A1 | HYPOPHOSPHOROUS ACID DERIVATIVES HAVING ANTIHYPERALGIC ACTIVITY AND BIOLOGICAL APPLICATIONS THEREOF | UNIVWESITE D"AUVERGNE (FR) | 2014-04-17 | — | — | US | disclosed |
| WO-2012156931-A1 | HYPOPHOSPHOROUS ACID DERIVATIVES HAVING ANTIHYPERALGIC ACTIVITY AND BIOLOGICAL APPLICATIONS THEREOF | UNIVERSITE PARIS DESCARTES (FR) | 2012-11-22 | — | — | WO | disclosed |
| US-7435841-B2 | Preparation of halohydrocarbyl phosphonic acid diesters | RHODIA INC. (US) | 2008-10-14 | — | — | US | disclosed |
| WO-2005086961-A2 | IMPROVED PREPARATION OF HALOHYDROCCARBYL PHOSPHONIC ACID DIESTRES | RHODIA INC. (US) | 2005-09-22 | — | — | WO | disclosed |
| US-20050203306-A1 | Preparation of halohydrocarbyl phosphonic acid diesters | RHODIA OPERATIONS (FR) | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203306-A1 | Preparation of halohydrocarbyl phosphonic acid diesters | HDHD5, PHYKPL, HPD | CTSA 4304/4885ACHE 1857/4885HMGCR 585/4885 |
| US-20140107078-A1 | HYPOPHOSPHOROUS ACID DERIVATIVES HAVING ANTIHYPERALGIC ACTIVITY AND BIOLOGICAL APPLICATIONS THEREOF | HCAR3, HRH3, SSTR3 | CTSA 1961/4885ACHE 951/4885HMGCR 2447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.