Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | LAP3 | P28838 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381492 | 0.96 | TSHR (0.57) | TSHRMEN1HTTKMT2ASRC | |
| SCHEMBL6862381 | 0.92 | TSHR (0.52) | TSHRMEN1HTTKMT2ASRC | |
| SCHEMBL13875357 | 0.90 | TSHR (0.55) | TSHRMEN1KMT2ASRCNR4A1 | |
| SCHEMBL8519323 | 0.89 | TSHR (0.50) | TSHRMEN1HTTKMT2ASRC | |
| SCHEMBL27726043 | 0.89 | TSHR (0.50) | TSHRMEN1HTTKMT2ASRC | |
| SCHEMBL2987983 | 0.88 | NR4A2 (0.65) | TSHRMEN1KMT2ANR4A1NR4A2 | |
| SCHEMBL6862483 | 0.87 | TSHR (0.47) | TSHRMEN1HTTKMT2ASRC | |
| SCHEMBL28671897 | 0.86 | TSHR (0.47) | TSHRMEN1HTTKMT2ASRC | |
| SCHEMBL21419139 | 0.86 | TSHR (0.51) | TSHRSRCNR4A1NR4A2NR4A3 | |
| SCHEMBL4220649 | 0.86 | NR4A2 (0.63) | TSHRMEN1KMT2ANR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103347859-A | Synthesis and Anticancer Activity of Aryl and Heteroaryl Quinoline Derivatives | EFFICIENT PHARMA MAN CORP | 2013-10-09 | — | — | CN | claimed |
| CN-115725123-A | Method for incorporating graphene into rubber complexes using a liquid plasticizer route-LPR method | 福特全球技术公司 | 2023-03-03 | — | — | CN | disclosed |
| EP-0531000-A1 | Oil additive concentrates and lubricants of enhanced performance capabilities | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1993-03-10 | — | — | EP | disclosed |
| EP-0493928-A1 | Lubricating oil compositions, concentrates and the use thereof | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-07-08 | — | — | EP | disclosed |