SCHEMBL381492

SCHEMBL381492

O=P(OCc1ccccc1)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.57
MEN1 O00255 1/20 0.50
HTT P42858 1/20 0.50
KMT2A Q03164 1/20 0.50
SRC P12931 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
ANPEP P15144 1/20 0.45
LAP3 P28838 1/20 0.45
CETP P11597 3/20 0.44
ELANE P08246 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568480 0.96 TSHR (0.57) TSHRMEN1HTTKMT2ASRC
SCHEMBL6862381 0.96 TSHR (0.52) TSHRMEN1HTTKMT2ASRC
SCHEMBL6862483 0.91 TSHR (0.47) TSHRMEN1HTTKMT2ASRC
SCHEMBL8519323 0.89 TSHR (0.50) TSHRMEN1HTTKMT2ASRC
SCHEMBL15283147 0.88 TSHR (0.53) TSHRMEN1KMT2A
SCHEMBL28468606 0.88 MEN1 (0.49) TSHRMEN1KMT2ASRC
SCHEMBL28468508 0.88 L3MBTL1 (0.48) TSHRMEN1KMT2AL3MBTL1
SCHEMBL13875357 0.86 TSHR (0.55) TSHRMEN1KMT2ASRCCETP
SCHEMBL28671897 0.86 TSHR (0.47) TSHRMEN1HTTKMT2ASRC
SCHEMBL206609 0.85 TSHR (0.68) TSHRSRCCETPELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 517 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119101547-A Refrigerator oil and application thereof 北京福润联石化科技开发有限公司 2024-12-10 CN claimed
CN-115052957-B Refrigerator oil composition and refrigerator mixed composition 出光兴产株式会社 2024-08-23 CN claimed
CN-115109632-B Refrigerating machine oil used with low-molecular hydrocarbon refrigerant and application thereof 北京福润联石化科技开发有限公司 2023-08-25 CN claimed
CN-110997884-B Metal working oil composition and method for producing metal sheet laminate 出光兴产株式会社 2023-06-20 CN claimed
CN-115109630-B Refrigerator oil composition used in cooperation with difluoromethane refrigerant and application thereof 北京福润联石化科技开发有限公司 2023-01-17 CN claimed
CN-109477014-B Refrigerator oil and composition for refrigerator 出光兴产株式会社 2022-11-01 CN claimed
CN-115109630-A Refrigerator oil composition used in combination with difluoromethane refrigerant and application thereof 北京福润联石化科技开发有限公司 2022-09-27 CN claimed
CN-107429183-B Lubricating oil composition 出光兴产株式会社 2021-03-19 CN claimed
EP-3421794-B1 REFRIGERATION APPARATUS DAIKIN IND LTD (JP) 2020-08-05 EP claimed
EP-3421794-A1 REFRIGERATION APPARATUS Daikin Industries, Ltd. (JP) 2019-01-02 EP claimed
US-7527902-B2 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION (US) 2009-05-05 US claimed
US-20070026328-A1 Photoreceptor layer having phosphorus-containing lubricant XEROX CORPORATION 2007-02-01 US claimed
US-20070026330-A1 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION 2007-02-01 US claimed
JP-7097589-A None JP disclosed
CN-116659004-B Air conditioner DAIKIN INDUSTRIES, LTD. (JP) 2026-05-26 CN disclosed
US-20260109911-A1 FRICTION MODIFIER FOR WET CLUTCH CHEVRON ORONITE CO (US) 2026-04-23 US disclosed
EP-0465156-A2 A hydraulic, lubricating and coupling composition comprising an organopolysiloxane and a phosphorus-containing anti-wear additive Tonen Corporation (JP) 1992-01-08 EP disclosed
EP-0462777-A2 A hydraulic, lubricating and coupling composition Tonen Corporation (JP) 1991-12-27 EP disclosed
EP-0397507-A1 Silicone fluids for viscous couplings Tonen Corporation (JP) 1990-11-14 EP disclosed
JP-H00797589-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109911-A1 FRICTION MODIFIER FOR WET CLUTCH SMCHD1, CLTC, CLTA TSHR 3800/4885MEN1 4550/4885HTT 2931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.