Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 2/20 | 0.58 |
| ▸ | AURKA | O14965 | 1/20 | 0.58 |
| ▸ | TTR | P02766 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | COMT | P21964 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | CHAT | P28329 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.39 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.39 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | ATIC | P31939 | 3/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | EEF2K | O00418 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568585 | 1.00 | AURKB (0.58) | AURKBAURKATTRCYP1A2COMT | |
| SCHEMBL9568598 | 0.96 | AURKB (0.58) | AURKBAURKATTRCYP1A2COMT | |
| SCHEMBL9568549 | 0.96 | AURKB (0.58) | AURKBAURKATTRCYP1A2COMT | |
| SCHEMBL30167073 | 0.90 | AURKA (0.53) | AURKBAURKATTRCYP1A2COMT | |
| SCHEMBL8150051 | 0.90 | AURKA (0.53) | AURKBAURKATTRCYP1A2COMT | |
| Ammonia Solution, Strong SCHEMBL27832685 | 0.83 | AURKA (0.49) | AURKBAURKATTRCYP1A2COMT | |
| SCHEMBL592126 | 0.82 | AURKA (0.49) | AURKBAURKATTRCYP1A2COMT | |
| SCHEMBL18205264 | 0.82 | AURKA (0.49) | AURKBAURKATTRCYP1A2COMT | |
| SCHEMBL10903980 | 0.82 | AURKB (0.72) | AURKBAURKATTRCYP1A2COMT | |
| SCHEMBL27783050 | 0.82 | AURKA (0.49) | AURKBAURKATTRCYP1A2COMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548616-A1 | Aqueous chemiluminescent systems | AMERICAN CYANAMID COMPANY (US) | 1993-06-30 | — | — | EP | disclosed |
| EP-0034261-B1 | AQUEOUS CHEMILUMINESCENT SYSTEMS | AMERICAN CYANAMID COMPANY (US) | 1985-05-22 | — | — | EP | disclosed |
| US-4338213-A | Aqueous chemiluminescent systems | AMERICAN CYANAMID COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| EP-0034261-A2 | Aqueous chemiluminescent systems | AMERICAN CYANAMID COMPANY (US) | 1981-08-26 | — | — | EP | disclosed |
| US-4282357-A | SALTS OF N,N'-BIS(MORPHOLINO- OR PYRIDYLALKYL)-N,N'-BIS(TRIFLUOROMETHYLSULFONYL)OXAMIDES | AMERICAN CYANAMID COMPANY (US) | 1981-08-04 | — | — | US | disclosed |