Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | QDPR | P09417 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | INMT | O95050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568917 | 0.95 | QDPR (0.38) | CHRNB2CHRNA4QDPR | |
| SCHEMBL8730559 | 0.87 | QDPR (0.41) | QDPR | |
| Oxalic Acid SCHEMBL9569051 | 0.84 | QDPR (0.37) | CHRNB2CHRNA4QDPRHTR6 | |
| SCHEMBL9568964 | 0.83 | QDPR (0.36) | QDPRHTR6 | |
| SCHEMBL9103505 | 0.82 | QDPR (0.40) | QDPRHTR6 | |
| Hydrochloric Acid SCHEMBL11084396 | 0.80 | QDPR (0.39) | QDPRHTR6 | |
| SCHEMBL9568968 | 0.78 | QDPR (0.40) | QDPR | |
| SCHEMBL11084386 | 0.77 | QDPR (0.39) | QDPR | |
| SCHEMBL14340657 | 0.77 | QDPR (0.39) | QDPR | |
| SCHEMBL10088648 | 0.76 | AKT1 (0.37) | QDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537993-A1 | Nicotinic activity of a series of arecolones and isoarecolones | ELI LILLY AND COMPANY (US) | 1993-04-21 | — | — | EP | disclosed |