Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12616854 | 0.85 | ADORA1 (0.37) | CHRNB2CHRNA4ADORA1KDM4EALDH1A1 | |
| SCHEMBL12616900 | 0.74 | KDM4E (0.41) | CHRNB2CHRNA4ADORA1KDM4EALDH1A1 | |
| SCHEMBL8264794 | 0.73 | MAOA (0.38) | CHRNB2CHRNA4MAOAMAOB | |
| SCHEMBL18842323 | 0.71 | FFAR3 (0.31) | CHRNB2CHRNA4 | |
| SCHEMBL4738201 | 0.70 | KDM4E (0.33) | KDM4EGLA | |
| SCHEMBL23203639 | 0.67 | MAOA (0.33) | MAOAMAOB | |
| SCHEMBL14419210 | 0.66 | MEN1 (0.36) | ALDH1A1MEN1KMT2AMAOAMAOB | |
| SCHEMBL21134511 | 0.65 | MAOA (0.32) | MAOAMAOB | |
| SCHEMBL23202561 | 0.65 | MAOA (0.32) | MAOAMAOB | |
| SCHEMBL14885183 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537993-A1 | Nicotinic activity of a series of arecolones and isoarecolones | ELI LILLY AND COMPANY (US) | 1993-04-21 | — | — | EP | disclosed |