Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.69 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9568921 | 0.92 | CHRNB2 (0.67) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL9569029 | 0.89 | CHRNB2 (0.75) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL9569057 | 0.87 | CHRNB2 (0.73) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL10738007 | 0.76 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL9502363 | 0.75 | CHRNB2 (0.59) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL9504121 | 0.74 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL9504116 | 0.74 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL9568916 | 0.73 | CHRNB2 (0.66) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| Fumaric Acid SCHEMBL9569039 | 0.73 | CHRNB2 (0.56) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL28238341 | 0.72 | HDAC4 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537993-A1 | Nicotinic activity of a series of arecolones and isoarecolones | ELI LILLY AND COMPANY (US) | 1993-04-21 | — | — | EP | disclosed |