Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2870972 | 0.84 | CALM1 (0.46) | HTR2ACALM1BCL2BCL2L1CYP3A4 | |
| SCHEMBL7735333 | 0.80 | CALM1 (0.55) | HTR2ACALM1BCL2BCL2L1CYP3A4 | |
| SCHEMBL10360527 | 0.76 | HTR2A (0.54) | HTR2ACALM1BCL2BCL2L1CYP3A4 | |
| SCHEMBL1046166 | 0.73 | CALM1 (0.58) | HTR2ACALM1BCL2BCL2L1CYP3A4 | |
| SCHEMBL29532678 | 0.72 | IDH1 (0.47) | HTR2ACALM1BCL2BCL2L1CYP3A4 | |
| SCHEMBL9719201 | 0.72 | IDH1 (0.47) | HTR2ACALM1BCL2BCL2L1CYP3A4 | |
| SCHEMBL146769 | 0.72 | IDH1 (0.47) | HTR2ACALM1BCL2BCL2L1CYP3A4 | |
| SCHEMBL1838403 | 0.71 | BCL2 (0.57) | HTR2ACALM1BCL2BCL2L1CYP3A4 | |
| SCHEMBL7033288 | 0.71 | HPGD (0.49) | HTR2ACALM1BCL2BCL2L1CYP3A4 | |
| SCHEMBL9419606 | 0.71 | CALM1 (0.44) | HTR2ACALM1BCL2BCL2L1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565450-A1 | Use of peptide derivatives for the manufacture of medicaments inhibiting endopeptidases 24.15 and 24.16 | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1993-10-13 | — | — | EP | disclosed |