Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | USP30 | Q70CQ3 | 13/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30172750 | 0.88 | MEN1 (0.58) | MEN1KMT2AUSP30 | |
| SCHEMBL16993944 | 0.88 | USP30 (0.56) | MEN1KMT2AUSP30CTSLCTSS | |
| SCHEMBL16993989 | 0.88 | MEN1 (0.58) | MEN1KMT2AUSP30 | |
| SCHEMBL16999274 | 0.87 | USP30 (0.57) | MEN1KMT2AUSP30CTSLCTSS | |
| SCHEMBL16993928 | 0.87 | USP30 (0.57) | MEN1KMT2AUSP30CTSLCTSS | |
| SCHEMBL16999623 | 0.84 | USP30 (0.54) | MEN1KMT2AUSP30CYP1A2CYP3A4 | |
| SCHEMBL17913121 | 0.84 | MEN1 (0.66) | MEN1KMT2AUSP30 | |
| SCHEMBL16999330 | 0.84 | USP30 (0.59) | MEN1KMT2AUSP30 | |
| SCHEMBL16994008 | 0.84 | USP30 (0.59) | MEN1KMT2AUSP30 | |
| SCHEMBL16993945 | 0.83 | CTSL (0.59) | USP30NPC1RAB9ACTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549264-A1 | Purified para-nitrobenzyl esterase from bacillus | OKLAHOMA STATE UNIVERSITY (US) | 1993-06-30 | — | — | EP | disclosed |