Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | CLK2 | P49760 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 14/20 | 0.46 |
| ▸ | TOP2B | Q02880 | 13/20 | 0.46 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569186 | 0.92 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9560791 | 0.85 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9569179 | 0.83 | TOP2A (0.47) | KDM4EALDH1A1TOP2ATOP2BTOP1 | |
| SCHEMBL9569188 | 0.83 | TOP1 (0.41) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL9560217 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9560796 | 0.77 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9560755 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9560276 | 0.76 | TOP2A (0.57) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9569190 | 0.74 | TOP1 (0.33) | TOP2ATOP2BTOP1 | |
| SCHEMBL9560445 | 0.74 | KDM4E (0.64) | KDM4EALDH1A1HPGDHSD17B10PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563734-A1 | 9-fluoro-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazine carboxylic acids and esters and their use as antiviral agents | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |