Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569217 | 0.88 | KDM4E (0.37) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9262366 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9569224 | 0.76 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9569215 | 0.75 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9626398 | 0.74 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL1878010 | 0.73 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10CSNK2A2 | |
| SCHEMBL9538007 | 0.73 | LMNA (0.36) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL10755601 | 0.73 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL11258062 | 0.72 | CSNK2A1 (0.52) | KDM4EALDH1A1HPGDHSD17B10CSNK2A2 | |
| SCHEMBL9569209 | 0.72 | HPGD (0.46) | KDM4EALDH1A1HPGDHSD17B10CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541086-A1 | Antibacterial 6-fluoro-quinolones having an oxime group on the substituent in position 7 | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-05-12 | — | — | EP | disclosed |