Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.40 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | DNA2 | P51530 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569200 | 0.89 | HPGD (0.46) | HPGDKDM4EALDH1A1CSNK2A2CSNK2B | |
| SCHEMBL9569241 | 0.85 | HPGD (0.45) | HPGDKDM4EALDH1A1CSNK2A2CSNK2B | |
| SCHEMBL9569209 | 0.81 | HPGD (0.46) | HPGDKDM4EALDH1A1CSNK2A2CSNK2B | |
| SCHEMBL9569233 | 0.77 | HPGD (0.43) | HPGDKDM4EALDH1A1CSNK2A2CSNK2B | |
| SCHEMBL9569226 | 0.77 | KDM4E (0.43) | HPGDKDM4EALDH1A1CSNK2A2CSNK2B | |
| SCHEMBL16011743 | 0.71 | KDM4E (0.42) | HPGDKDM4EALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL9569240 | 0.68 | KDM4E (0.41) | HPGDKDM4EALDH1A1HSD17B10KCNH2 | |
| SCHEMBL7509122 | 0.67 | KDM4E (1.00) | HPGDKDM4EALDH1A1CSNK2A2CSNK2B | |
| Hydrochloric Acid SCHEMBL30353212 | 0.66 | ALDH1A1 (0.97) | HPGDKDM4EALDH1A1CSNK2A2CSNK2B | |
| Ammonia Solution, Strong SCHEMBL28187483 | 0.66 | ALDH1A1 (0.97) | HPGDKDM4EALDH1A1CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541086-A1 | Antibacterial 6-fluoro-quinolones having an oxime group on the substituent in position 7 | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-05-12 | — | — | EP | disclosed |