Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6401686 | 0.99 | TPSAB1 (0.34) | TPSAB1TPSD1TPSG1HPGDMAPT | |
| SCHEMBL5982410 | 0.81 | HPGD (0.45) | TPSAB1TPSD1TPSG1HPGDALDH1A1 | |
| SCHEMBL5983070 | 0.81 | HPGD (0.45) | TPSAB1TPSD1TPSG1HPGDALDH1A1 | |
| SCHEMBL5982386 | 0.81 | HPGD (0.45) | TPSAB1TPSD1TPSG1HPGDALDH1A1 | |
| SCHEMBL5982461 | 0.79 | GLA (0.43) | TPSAB1TPSD1TPSG1HPGDALDH1A1 | |
| SCHEMBL5982713 | 0.78 | HPGD (0.32) | HPGDMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL9136130 | 0.78 | HPGD (0.32) | HPGDMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL5982318 | 0.76 | TPSAB1 (0.38) | TPSAB1TPSD1TPSG1HPGDMAPT | |
| SCHEMBL5982578 | 0.76 | TPSAB1 (0.38) | TPSAB1TPSD1TPSG1HPGDMAPT | |
| SCHEMBL5982685 | 0.76 | TPSAB1 (0.38) | TPSAB1TPSD1TPSG1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560330-A2 | Substituted benzimidazolyl derivatives, therapeutic agents containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-09-15 | — | — | EP | disclosed |