Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CDA | P32320 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569374 | 0.89 | CCNA2 (0.35) | PDE4DPDE3ASLC29A1ENPP1CCNA2 | |
| SCHEMBL9569349 | 0.85 | PDE4D (0.34) | PDE4DPDE3ASLC29A1 | |
| SCHEMBL8713050 | 0.84 | PDE4D (0.37) | PDE4DPDE3ASLC29A1CDA | |
| SCHEMBL9569318 | 0.83 | PDE4D (0.34) | PDE4DPDE3ASLC29A1CDK2 | |
| SCHEMBL9569319 | 0.83 | PDE4D (0.32) | PDE4DPDE3ASLC29A1 | |
| SCHEMBL9569360 | 0.83 | ADORA3 (0.36) | PDE4DPDE3ASLC29A1 | |
| SCHEMBL9569350 | 0.80 | PDE4D (0.32) | PDE4DPDE3ASLC29A1 | |
| SCHEMBL9569342 | 0.79 | PDE4D (0.33) | PDE4DPDE3ASLC29A1 | |
| SCHEMBL9569323 | 0.74 | PDE4D (0.36) | PDE4DPDE3ASLC29A1CDA | |
| SCHEMBL9569363 | 0.66 | GRIN2B (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576227-A2 | 2'-Deoxy-2',2'-difluoro(2,6,8-substituted) purine nucleosides having anti-viral and anti-cancer activity and intermediates | ELI LILLY AND COMPANY (US) | 1993-12-29 | — | — | EP | claimed |
| EP-0576227-A2 | 2'-Deoxy-2',2'-difluoro(2,6,8-substituted) purine nucleosides having anti-viral and anti-cancer activity and intermediates | ELI LILLY AND COMPANY (US) | 1993-12-29 | — | — | EP | disclosed |