Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 5/20 | 0.56 |
| ▸ | HPRT1 | P00492 | 11/20 | 0.54 |
| ▸ | TK1 | P04183 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569460 | 1.00 | PNP (0.56) | PNPHPRT1TK1POLB | |
| SCHEMBL9569450 | 0.86 | HPRT1 (0.60) | PNPHPRT1TK1 | |
| SCHEMBL9569446 | 0.86 | HPRT1 (0.60) | PNPHPRT1TK1 | |
| SCHEMBL9569453 | 0.81 | BLM (0.61) | PNPHPRT1 | |
| SCHEMBL9569457 | 0.81 | BLM (0.61) | PNPHPRT1 | |
| SCHEMBL9569526 | 0.81 | ADORA2A (0.50) | — | |
| SCHEMBL9569515 | 0.81 | ADORA2A (0.50) | — | |
| SCHEMBL9569537 | 0.81 | ADORA2A (0.50) | — | |
| SCHEMBL10916532 | 0.77 | HPRT1 (0.57) | PNPHPRT1TK1 | |
| SCHEMBL7173165 | 0.77 | TK1 (0.68) | PNPHPRT1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532423-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |