Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.47 |
| ▸ | AHCY | P23526 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | POLA1 | P09884 | 1/20 | 0.43 |
| ▸ | POLG | P54098 | 1/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569546 | 1.00 | ADORA2A (0.48) | ADORA2AADORA1ADORA2BFGFR1SLC22A6 | |
| SCHEMBL9569538 | 1.00 | ADORA2A (0.48) | ADORA2AADORA1ADORA2BFGFR1SLC22A6 | |
| SCHEMBL9569537 | 0.88 | ADORA2A (0.50) | ADORA2AADORA1ADORA2BFGFR1SLC22A6 | |
| SCHEMBL9569515 | 0.88 | ADORA2A (0.50) | ADORA2AADORA1ADORA2BFGFR1SLC22A6 | |
| SCHEMBL9569526 | 0.88 | ADORA2A (0.50) | ADORA2AADORA1ADORA2BFGFR1SLC22A6 | |
| SCHEMBL9569753 | 0.86 | ADORA2A (0.54) | ADORA2AADORA1ADORA2BFGFR1SLC22A6 | |
| SCHEMBL9569758 | 0.86 | ADORA2A (0.54) | ADORA2AADORA1ADORA2BFGFR1SLC22A6 | |
| SCHEMBL9569750 | 0.86 | ADORA2A (0.54) | ADORA2AADORA1ADORA2BFGFR1SLC22A6 | |
| SCHEMBL9569488 | 0.82 | CYP3A4 (0.48) | ADORA2AADORA1AHCYCYP3A4PI4KA | |
| SCHEMBL9569502 | 0.82 | CYP3A4 (0.48) | ADORA2AADORA1AHCYCYP3A4PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532423-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |