Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | AHCY | P23526 | 8/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569758 | 1.00 | ADORA2A (0.54) | ADORA2AADORA1FGFR1SLC22A6AHCY | |
| SCHEMBL9569750 | 1.00 | ADORA2A (0.54) | ADORA2AADORA1FGFR1SLC22A6AHCY | |
| SCHEMBL9294953 | 0.89 | AHCY (0.58) | ADORA2AADORA1FGFR1SLC22A6AHCY | |
| SCHEMBL9294967 | 0.89 | AHCY (0.58) | ADORA2AADORA1FGFR1SLC22A6AHCY | |
| SCHEMBL9569748 | 0.86 | FGFR1 (0.55) | ADORA2AADORA1FGFR1SLC22A6AHCY | |
| SCHEMBL9569751 | 0.86 | FGFR1 (0.55) | ADORA2AADORA1FGFR1SLC22A6AHCY | |
| SCHEMBL9569755 | 0.86 | FGFR1 (0.55) | ADORA2AADORA1FGFR1SLC22A6AHCY | |
| SCHEMBL9569546 | 0.86 | ADORA2A (0.48) | ADORA2AADORA1FGFR1SLC22A6AHCY | |
| SCHEMBL9569538 | 0.86 | ADORA2A (0.48) | ADORA2AADORA1FGFR1SLC22A6AHCY | |
| SCHEMBL9569562 | 0.86 | ADORA2A (0.48) | ADORA2AADORA1FGFR1SLC22A6AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532423-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | claimed |