Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569608 | 1.00 | PPARD (0.43) | PPARDTSHRLPAR3TP53TDP1 | |
| SCHEMBL31519202 | 0.83 | TSHR (0.40) | PPARDTSHRLPAR3TP53TDP1 | |
| SCHEMBL17635917 | 0.83 | PPARD (0.41) | PPARDTSHRLPAR3TP53TDP1 | |
| SCHEMBL8658471 | 0.79 | LPAR3 (0.47) | TSHRLPAR3TP53TDP1LPAR2 | |
| SCHEMBL8658473 | 0.79 | LPAR3 (0.47) | TSHRLPAR3TP53TDP1LPAR2 | |
| SCHEMBL14457784 | 0.79 | AOX1 (0.39) | PPARDTSHRLPAR3TP53TDP1 | |
| SCHEMBL9569719 | 0.79 | TSHR (0.37) | PPARDTSHRLPAR3TP53TDP1 | |
| SCHEMBL14457780 | 0.79 | TSHR (0.37) | PPARDTSHRLPAR3TP53TDP1 | |
| SCHEMBL9569716 | 0.79 | TSHR (0.37) | PPARDTSHRLPAR3TP53TDP1 | |
| SCHEMBL22734073 | 0.78 | CA1 (0.32) | CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532423-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |