Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569530 | 0.79 | LPAR3 (0.32) | LPAR3LPAR2LPAR1 | |
| SCHEMBL9569609 | 0.78 | KDM4E (0.48) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL9569604 | 0.78 | KDM4E (0.48) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL9569727 | 0.76 | — | — | |
| SCHEMBL9569627 | 0.76 | — | — | |
| SCHEMBL9569624 | 0.72 | TSHR (0.45) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL9569615 | 0.72 | TSHR (0.45) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL11342686 | 0.69 | SMPD1 (0.32) | — | |
| SCHEMBL10498122 | 0.69 | ALDH1A1 (0.42) | ALDH1A1TSHRLPAR3LPAR2LPAR1 | |
| SCHEMBL14777063 | 0.68 | KDM4E (0.30) | KDM4EUSP2ALDH1A1LMNAMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532423-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |