Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 9/20 | 0.58 |
| ▸ | PNP | P00491 | 8/20 | 0.57 |
| ▸ | TK1 | P04183 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | VCP | P55072 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569605 | 1.00 | HPRT1 (0.58) | HPRT1PNPTK1MEN1ALDH1A1 | |
| SCHEMBL9294938 | 0.90 | HPRT1 (0.60) | HPRT1PNPTK1MEN1ALDH1A1 | |
| SCHEMBL9294925 | 0.90 | HPRT1 (0.60) | HPRT1PNPTK1MEN1ALDH1A1 | |
| SCHEMBL9569446 | 0.88 | HPRT1 (0.60) | HPRT1PNPTK1 | |
| SCHEMBL9569450 | 0.88 | HPRT1 (0.60) | HPRT1PNPTK1 | |
| SCHEMBL10508111 | 0.85 | TK1 (0.63) | HPRT1PNPTK1MEN1ALDH1A1 | |
| Penciclovir SCHEMBL454090 | 0.84 | HPRT1 (0.66) | HPRT1PNPTK1MEN1ALDH1A1 | |
| Penciclovir SCHEMBL4240104 | 0.84 | HPRT1 (0.66) | HPRT1PNPTK1MEN1ALDH1A1 | |
| Buciclovir SCHEMBL571385 | 0.82 | HPRT1 (0.67) | HPRT1PNPTK1MEN1ALDH1A1 | |
| SCHEMBL9295547 | 0.82 | HPRT1 (0.50) | HPRT1PNPMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532423-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | claimed |