Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 13/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569467 | 0.88 | HPRT1 (0.52) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9294933 | 0.82 | HPRT1 (0.62) | HPRT1PNP | |
| SCHEMBL9569639 | 0.81 | HPRT1 (0.56) | HPRT1PNP | |
| SCHEMBL147641 | 0.81 | HPRT1 (0.67) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL8896070 | 0.81 | HPRT1 (0.74) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9569709 | 0.80 | HPRT1 (0.59) | HPRT1ALDH1A1BLMKMT2APNP | |
| SCHEMBL7132437 | 0.80 | HPRT1 (0.60) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| Phosphoric Acid SCHEMBL9471917 | 0.78 | HPRT1 (0.59) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9569464 | 0.78 | HPRT1 (0.58) | HPRT1ALDH1A1BLMKMT2APNP | |
| SCHEMBL9295538 | 0.78 | HPRT1 (0.51) | HPRT1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532423-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | claimed |