Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 13/20 | 0.59 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PAH | P00439 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569464 | 0.89 | HPRT1 (0.58) | HPRT1PNPNOS1USP2CASP7 | |
| SCHEMBL9294933 | 0.87 | HPRT1 (0.62) | HPRT1PNP | |
| SCHEMBL9569639 | 0.81 | HPRT1 (0.56) | HPRT1PNP | |
| SCHEMBL21638909 | 0.81 | HPRT1 (0.65) | HPRT1NOS1USP2CASP7HSD17B10 | |
| SCHEMBL21638902 | 0.81 | HPRT1 (0.65) | HPRT1NOS1USP2CASP7HSD17B10 | |
| SCHEMBL9569647 | 0.80 | HPRT1 (0.59) | HPRT1PNPALDH1A1BLMKMT2A | |
| SCHEMBL9295431 | 0.80 | HPRT1 (0.62) | HPRT1PNPNOS1 | |
| SCHEMBL20509480 | 0.79 | HPRT1 (0.62) | HPRT1NOS1USP2CASP7HSD17B10 | |
| SCHEMBL6833417 | 0.78 | HPRT1 (0.58) | HPRT1PNPNOS1 | |
| SCHEMBL7142937 | 0.77 | HPRT1 (0.64) | HPRT1NOS1USP2CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532423-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | claimed |