Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29165133 | 1.00 | TSHR (0.69) | TSHRALDH1A1DNM1MAPTSIGMAR1 | |
| SCHEMBL31154544 | 1.00 | TSHR (0.69) | TSHRALDH1A1DNM1MAPTSIGMAR1 | |
| SCHEMBL6446892 | 1.00 | TSHR (0.69) | TSHRALDH1A1DNM1MAPTSIGMAR1 | |
| SCHEMBL6443829 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL29063477 | 0.97 | ALDH1A1 (0.65) | TSHRALDH1A1DNM1MAPTSIGMAR1 | |
| Hydrochloric Acid SCHEMBL29063506 | 0.97 | ALDH1A1 (0.65) | TSHRALDH1A1DNM1MAPTSIGMAR1 | |
| Hydrochloric Acid SCHEMBL29063587 | 0.97 | ALDH1A1 (0.65) | TSHRALDH1A1DNM1MAPTSIGMAR1 | |
| Hydrochloric Acid SCHEMBL10478935 | 0.97 | ALDH1A1 (0.65) | TSHRALDH1A1DNM1MAPTSIGMAR1 | |
| Hydrochloric Acid SCHEMBL29063593 | 0.97 | ALDH1A1 (0.65) | TSHRALDH1A1DNM1MAPTSIGMAR1 | |
| SCHEMBL6187154 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558094-A1 | Pyridine compounds for treating amnesia | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |