Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9569844 | 0.98 | NPC1 (0.30) | NPC1GAARAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL23302243 | 0.77 | SMN1; SMN2 (0.35) | NPC1GAARAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL13169127 | 0.77 | NPC1 (0.32) | NPC1GAARAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL15918185 | 0.70 | NPC1 (0.33) | NPC1GAARAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL24114852 | 0.61 | — | — | |
| Trifluoroacetic Acid SCHEMBL9569208 | 0.61 | ALDH1A1 (0.33) | NPC1GAARAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL1219152 | 0.60 | — | — | |
| SCHEMBL11211865 | 0.60 | — | — | |
| SCHEMBL9569879 | 0.60 | — | — | |
| Fluoride SCHEMBL28750147 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227500-A | Halogenated 1,3-dioxolanes and derivatives | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-07-13 | — | — | US | disclosed |
| EP-0529741-A1 | Procedure for the preparation of halogenated 1,3-dioxolanes | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-03-03 | — | — | EP | disclosed |
| US-5057586-A | Fluoropolymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-15 | — | — | US | disclosed |
| US-4973714-A | ADDITION POLYMERS, FLUOROPOLYMERS, HEAT RESISTANCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-11-27 | — | — | US | disclosed |
| US-4810806-A | FROM A HALOETHYL CARBOXYLATE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0301881-A1 | Halogenated 1,3-dioxolanes and derivatives | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-02-01 | — | — | EP | disclosed |