Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27450443 | 0.79 | CTH (0.32) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL27777420 | 0.75 | — | — | |
| SCHEMBL27540564 | 0.74 | — | — | |
| SCHEMBL777072 | 0.72 | TSHR (0.30) | TSHR | |
| SCHEMBL377483 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL27852757 | 0.67 | — | — | |
| SCHEMBL17760676 | 0.66 | TSHR (0.44) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL2865721 | 0.66 | — | — | |
| SCHEMBL777073 | 0.65 | HTT (0.31) | — | |
| SCHEMBL8217962 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529741-A1 | Procedure for the preparation of halogenated 1,3-dioxolanes | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-03-03 | — | — | EP | claimed |
| EP-0301881-A1 | Halogenated 1,3-dioxolanes and derivatives | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-02-01 | — | — | EP | claimed |
| EP-0529741-A1 | Procedure for the preparation of halogenated 1,3-dioxolanes | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-03-03 | — | — | EP | disclosed |