Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851482 | 0.83 | KDM4C (0.63) | KDM4CPOLBNPC1RAB9AAAK1 | |
| SCHEMBL9598111 | 0.83 | KDM4C (0.44) | KDM4CPOLBCHRM1NPC1RAB9A | |
| SCHEMBL8566027 | 0.80 | KDM4C (0.52) | KDM4CPOLBKMT2A | |
| SCHEMBL10650966 | 0.79 | POLB (0.51) | KDM4CPOLBKDM4EKMT2A | |
| SCHEMBL31875233 | 0.79 | CACNA1H (0.44) | KDM4CPOLBPDE3BPDE3AKRAS | |
| SCHEMBL10206036 | 0.79 | DDAH1 (0.59) | KDM4CPOLBPDE3BPDE3AHTT | |
| SCHEMBL5806722 | 0.79 | TDP1 (0.49) | KDM4CPOLBCHRM1NPC1RAB9A | |
| SCHEMBL7578581 | 0.79 | KDM4C (0.40) | KDM4CPOLBNPC1RAB9APDE3B | |
| SCHEMBL4072911 | 0.79 | CACNA1H (0.44) | KDM4CPOLBPDE3BPDE3AKRAS | |
| Hydrochloric Acid SCHEMBL27147079 | 0.77 | CACNA1H (0.42) | KDM4CPOLBPDE3BPDE3AKRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |
| EP-0555825-A1 | Imidazo(1,2-a)pyridines as angiotensin-II-antagonists | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |