Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19348779 | 0.80 | LPAR2 (0.31) | LPAR2LPAR3ALDH1A1 | |
| SCHEMBL14352148 | 0.80 | — | — | |
| SCHEMBL30605 | 0.79 | TSHR (0.38) | LPAR2LPAR3ALDH1A1TSHR | |
| SCHEMBL9231828 | 0.78 | — | — | |
| SCHEMBL3507987 | 0.77 | CYP3A4 (0.32) | LPAR2LPAR3ALDH1A1 | |
| SCHEMBL19348777 | 0.76 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL19348800 | 0.76 | — | — | |
| SCHEMBL4098208 | 0.76 | TSHR (0.32) | TSHR | |
| SCHEMBL15847030 | 0.74 | LPAR3 (0.50) | LPAR2LPAR3 | |
| SCHEMBL3203191 | 0.74 | TP53 (0.32) | LPAR2LPAR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | claimed |
| EP-0555825-A1 | Imidazo(1,2-a)pyridines as angiotensin-II-antagonists | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | claimed |
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |
| EP-0555825-A1 | Imidazo(1,2-a)pyridines as angiotensin-II-antagonists | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |
| US-4202816-A | ENOL-PIPERIDINE METAL COMPLEXES | CIBA-GEIGY CORPORATION (US) | 1980-05-13 | — | — | US | disclosed |