⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17688 | 0.78 | — | — | |
| SCHEMBL28138740 | 0.78 | ADORA1 (0.38) | — | |
| SCHEMBL3638029 | 0.77 | — | — | |
| SCHEMBL5439300 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL27901170 | 0.76 | — | — | |
| SCHEMBL1219898 | 0.76 | — | — | |
| SCHEMBL11854680 | 0.76 | — | — | |
| SCHEMBL9143102 | 0.76 | — | — | |
| SCHEMBL542826 | 0.76 | — | — | |
| SCHEMBL27353369 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |
| EP-0555825-A1 | Imidazo(1,2-a)pyridines as angiotensin-II-antagonists | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |