Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | FPR1 | P21462 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12743823 | 0.89 | CA1 (0.50) | CA1CA12CA2CA9LMNA | |
| SCHEMBL13630660 | 0.86 | CA1 (0.48) | CA1CA12CA2CA9LMNA | |
| SCHEMBL9597212 | 0.83 | CA1 (0.45) | CA1CA12CA2CA9LMNA | |
| SCHEMBL25984975 | 0.81 | CA1 (0.43) | CA1CA12CA2CA9LMNA | |
| SCHEMBL5210747 | 0.81 | CA1 (0.43) | CA1CA12CA2CA9LMNA | |
| SCHEMBL15218603 | 0.79 | CA12 (0.42) | CA1CA12CA2CA9LMNA | |
| SCHEMBL4146961 | 0.77 | CA1 (0.48) | CA1CA12CA2CA9LMNA | |
| SCHEMBL5208802 | 0.76 | CA1 (0.46) | CA1CA12CA2CA9LMNA | |
| SCHEMBL1116505 | 0.76 | CA12 (0.46) | CA1CA12CA2CA9LMNA | |
| SCHEMBL2975892 | 0.75 | LMNA (0.76) | CA1CA12CA9LMNACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |
| EP-0555825-A1 | Imidazo(1,2-a)pyridines as angiotensin-II-antagonists | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |