Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 2/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP9 | P55211 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Buquinolate SCHEMBL30589264 | 0.85 | DPP4 (0.45) | — | |
| Buquinolate SCHEMBL1404252 | 0.85 | DPP4 (0.45) | — | |
| SCHEMBL6143695 | 0.82 | EGFR (0.53) | EGFRERBB2NUDT1 | |
| SCHEMBL29365224 | 0.78 | EGFR (0.45) | EGFRERBB2NUDT1 | |
| SCHEMBL22589468 | 0.78 | EGFR (0.45) | EGFRERBB2NUDT1 | |
| SCHEMBL7071545 | 0.77 | PTPN11 (0.45) | TP53RXRA | |
| SCHEMBL2723767 | 0.75 | EGFR (0.50) | EGFRERBB2NUDT1 | |
| SCHEMBL3871505 | 0.75 | EGFR (0.50) | EGFRERBB2NUDT1 | |
| Proquinolate SCHEMBL1813584 | 0.74 | TSHR (0.46) | NUDT1 | |
| Hydrochloric Acid SCHEMBL6084967 | 0.74 | EGFR (0.49) | EGFRERBB2NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549263-A2 | A process for the preparation of N-alkyl-3,4-dialkyloxyanilines and derivatives thereof | CHEMAGIS LTD. (IL) | 1993-06-30 | — | — | EP | disclosed |