Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 6/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decoquinate SCHEMBL43853 | 0.88 | DPP4 (0.46) | HSD17B10 | |
| Decoquinate SCHEMBL29373625 | 0.88 | DPP4 (0.46) | HSD17B10 | |
| Decoquinate SCHEMBL14247781 | 0.86 | DPP4 (0.44) | HSD17B10 | |
| Decoquinate SCHEMBL14247780 | 0.85 | DPP4 (0.44) | HSD17B10 | |
| Decoquinate SCHEMBL10696854 | 0.84 | DPP4 (0.42) | HSD17B10ALDH1A1 | |
| SCHEMBL22589468 | 0.80 | EGFR (0.45) | ALDH1A1 | |
| SCHEMBL29365224 | 0.80 | EGFR (0.45) | ALDH1A1 | |
| Decoquinate SCHEMBL15152849 | 0.78 | LMNA (0.47) | PTPN11TSHRHSD17B10TP53ALDH1A1 | |
| SCHEMBL9555267 | 0.78 | PLA2G2A (0.38) | PTPN11S1PR3TSHRTP53PLA2G2A | |
| SCHEMBL9570459 | 0.77 | DHODH (0.48) | TP53RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828487-B1 | AGENTS FOR USE AGAINST PARASITIC PROTOZOA | BAYER AG (DE) | 2003-11-26 | — | — | EP | claimed |
| US-5200418-A | Orally administering decoquinate to neonatal bovine exposed and susceptivle to infection by cryptosporidium oocysts | THE OHIO STATE UNIVERSITY (US) | 1993-04-06 | — | — | US | disclosed |