SCHEMBL9570521

SCHEMBL9570521

Nc1ccc(C(=O)c2ccc3cc(S(=O)(=O)O)cc(O)c3c2N)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NT5E P21589 4/20 0.51
CASP6 P55212 3/20 0.49
CTDSP1 Q9GZU7 1/20 0.49
NSD2 O96028 2/20 0.48
DUSP3 P51452 1/20 0.48
PTPN5 P54829 1/20 0.48
PTPN11 Q06124 1/20 0.48
ENPP2 Q13822 1/20 0.42
APEX1 P27695 2/20 0.41
ALDH1A1 P00352 6/20 0.40
HSD17B10 Q99714 5/20 0.40
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
CA14 Q9ULX7 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
TSHR P16473 2/20 0.39
PRMT1 Q99873 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9570525 0.94 NT5E (0.49) NT5ECASP6CTDSP1NSD2DUSP3
SCHEMBL27455987 0.86 NT5E (0.48) NT5ECASP6CTDSP1NSD2DUSP3
SCHEMBL10386275 0.82 NT5E (0.51) NT5ECASP6CTDSP1NSD2DUSP3
SCHEMBL9551312 0.81 NT5E (0.53) NT5ECASP6CTDSP1NSD2DUSP3
SCHEMBL27429737 0.81 NT5E (0.50) NT5ECASP6CTDSP1NSD2DUSP3
SCHEMBL9570524 0.77 NT5E (0.55) NT5ECASP6CTDSP1NSD2DUSP3
SCHEMBL7791017 0.76 NT5E (0.65) NT5ECASP6CTDSP1NSD2DUSP3
Hydrochloric Acid SCHEMBL5736496 0.75 NT5E (0.63) NT5ECASP6CTDSP1NSD2DUSP3
SCHEMBL3912123 0.75 NT5E (0.58) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL9748497 0.74 APEX1 (0.55) NT5ECASP6CTDSP1NSD2DUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1235992-A Water-soluble fiber-reactive dyes, processes for their preparation and their use HOECHST AG (DE) 1999-11-24 CN disclosed
CN-1108674-A Water-soluble azo compounds, preparation thereof, and use thereof as dyes HOECHST AG (DE) 1995-09-20 CN disclosed
CN-1108277-A Water-soluble fibre-reactive dyes, their preparation and their use HOECHST AG (DE) 1995-09-13 CN disclosed
EP-0530106-A1 Dye-containing polarizing film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-03 EP disclosed