SCHEMBL7791017

SCHEMBL7791017

Nc1ccc2cc(S(=O)(=O)O)cc(O)c2c1N

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NT5E P21589 3/20 0.65
ALDH1A1 P00352 4/20 0.54
HSD17B10 Q99714 4/20 0.54
CASP6 P55212 4/20 0.54
CYP2C9 P11712 2/20 0.54
CYP2C19 P33261 2/20 0.54
NSD2 O96028 3/20 0.51
DUSP3 P51452 2/20 0.51
PTPN5 P54829 2/20 0.51
PTPN11 Q06124 2/20 0.51
SUMO2 P61956 1/20 0.47
SUMO1 P63165 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP2 Q9HC62 1/20 0.47
ENPP2 Q13822 2/20 0.46
CYP1A2 P05177 1/20 0.45
APEX1 P27695 2/20 0.43
HIF1A Q16665 1/20 0.42
CASP7 P55210 1/20 0.41
PRMT1 Q99873 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5736496 0.98 NT5E (0.63) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL27153180 0.87 NT5E (0.65) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL3912123 0.85 NT5E (0.58) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL9009313 0.84 NT5E (0.57) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL14001578 0.84 NT5E (0.61) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL8039915 0.81 NT5E (0.54) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL29495035 0.80 NT5E (0.56) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL14647834 0.80 NT5E (0.56) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL9570523 0.80 NT5E (0.53) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL9551312 0.80 NT5E (0.53) NT5EALDH1A1HSD17B10CASP6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3578162-B1 HAIR TREATMENT METHOD KAO CORP (JP) 2024-06-26 EP disclosed
EP-3626224-B1 MULTIAGENT-TYPE HAIR TREATMENT AGENT KAO CORP (JP) 2023-12-13 EP disclosed
WO-2023181691-A1 HAIR WASHING COMPOSITION 花王株式会社 2023-09-28 WO disclosed
CN-113811364-B Hair treatment method 花王株式会社 2023-09-05 CN disclosed
US-11523977-B2 Multi-agent type hair treatment agent KAO CORPORATION (JP) 2022-12-13 US disclosed
CN-110198702-B Hair treatment method 花王株式会社 2022-11-29 CN disclosed
US-20220226216-A1 HAIR TREATMENT METHOD KAO CORPORATION (JP) 2022-07-21 US disclosed
EP-3998060-A1 HAIR COSMETIC Kao Corporation (JP) 2022-05-18 EP disclosed
CN-114080217-A Hair cosmetic 花王株式会社 2022-02-22 CN disclosed
US-11234916-B2 Hair cosmetic KAO CORPORATION (JP) 2022-02-01 US disclosed
EP-0743847-B1 HAIR COSMETIC COMPOSITION KAO CORP (JP) 2001-05-30 EP disclosed
US-6217855-B1 ELASTICITY KAO CORPORATION (JP) 2001-04-17 US disclosed
EP-0662314-B1 Method of hair treatment KAO CORP (JP) 1999-11-03 EP disclosed
US-5683685-A NAPHTHALENESULFONIC ACID AND/OR BENZOPHENONE SULFONIC ACID WITH ANIONIC AND/OR AMPHOTERIC SURFACTANT WITH OIL KAO CORPORATION (JP) 1997-11-04 US disclosed
EP-0743847-A1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 1996-11-27 EP disclosed
EP-0529437-B1 Hair treatment composition KAO CORP (JP) 1996-07-17 EP disclosed
EP-0672405-A1 Hair treatment composition KAO CORPORATION (JP) 1995-09-20 EP disclosed
WO-1995020375-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 1995-08-03 WO disclosed
EP-0662314-A1 Method of hair treatment Kao Corporation (JP) 1995-07-12 EP disclosed
EP-0529437-A1 Hair treatment composition Kao Corporation (JP) 1993-03-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11523977-B2 Multi-agent type hair treatment agent POLR1C, SHH, PIK3C3 NT5E 3747/4885ALDH1A1 605/4885HSD17B10 1563/4885
US-20220226216-A1 HAIR TREATMENT METHOD POLR1C, ALDH7A1, CA7 NT5E 3725/4885ALDH1A1 6/4885HSD17B10 414/4885
US-11234916-B2 Hair cosmetic TYR, CUTA, H1-0 NT5E 4267/4885ALDH1A1 494/4885HSD17B10 222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.