Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | MPC2 | O95563 | 1/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570555 | 0.92 | CA2 (0.48) | PPARGFFAR1HRH3PPARAMAPT | |
| SCHEMBL13846795 | 0.87 | SLC2A1 (0.47) | PPARGFFAR1PPARACYP2C9MEN1 | |
| SCHEMBL8313024 | 0.86 | FFAR1 (0.64) | PPARGFFAR1HRH3PPARAMEN1 | |
| SCHEMBL13846788 | 0.85 | CNR2 (0.46) | PPARGFFAR1PPARATSHR | |
| SCHEMBL13846806 | 0.84 | CA2 (0.47) | PPARGFFAR1PPARAMAPT | |
| SCHEMBL13846718 | 0.84 | CNR2 (0.47) | PPARGFFAR1PPARATSHR | |
| SCHEMBL9570560 | 0.84 | FFAR1 (0.69) | PPARGFFAR1HRH3PPARAMPC2 | |
| SCHEMBL9570853 | 0.84 | FFAR1 (0.69) | PPARGFFAR1HRH3PPARAMPC2 | |
| SCHEMBL9570574 | 0.84 | FFAR1 (0.69) | PPARGFFAR1HRH3PPARAMPC2 | |
| SCHEMBL8957444 | 0.84 | FFAR1 (0.69) | PPARGFFAR1HRH3PPARAMPC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533933-A1 | BISHETEROCYCLIC COMPOUND | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |