Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | PPARG | P37231 | 7/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570606 | 0.90 | MAPT (0.69) | MAPTPPARGMAOACISD1ALDH1A1 | |
| SCHEMBL9570616 | 0.84 | MAPT (0.61) | MAPTPPARGMAOACISD1ALDH1A1 | |
| SCHEMBL290413 | 0.84 | MAPT (0.75) | MAPTPPARGMAOACISD1ALDH1A1 | |
| SCHEMBL9570681 | 0.84 | MAOB (0.69) | MAPTPPARGMAOACISD1ALDH1A1 | |
| SCHEMBL9570680 | 0.83 | MAPT (0.60) | MAPTPPARGMAOACISD1ALDH1A1 | |
| Glitazone SCHEMBL623021 | 0.83 | MAPT (0.73) | MAPTPPARGMAOACISD1ALDH1A1 | |
| SCHEMBL4852588 | 0.83 | MAPT (0.73) | MAPTPPARGMAOACISD1ALDH1A1 | |
| SCHEMBL5576600 | 0.81 | MAPT (0.71) | MAPTPPARGMAOACISD1ALDH1A1 | |
| SCHEMBL8857164 | 0.81 | MAPT (0.71) | MAPTPPARGMAOACISD1ALDH1A1 | |
| SCHEMBL1411677 | 0.81 | MAPT (0.71) | MAPTPPARGMAOACISD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533933-A1 | BISHETEROCYCLIC COMPOUND | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |