Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | PPARG | P37231 | 10/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570680 | 0.99 | MAPT (0.60) | MAPTPPARGHRH3FFAR1MAOA | |
| SCHEMBL9617824 | 0.92 | MAPT (0.53) | MAPTPPARGHRH3FFAR1MAOA | |
| SCHEMBL9570573 | 0.92 | HRH3 (0.60) | MAPTPPARGHRH3FFAR1ALDH1A1 | |
| SCHEMBL9570557 | 0.91 | HRH3 (0.58) | MAPTPPARGHRH3FFAR1ALDH1A1 | |
| SCHEMBL9374638 | 0.88 | PPARG (0.56) | MAPTPPARGHRH3FFAR1PPARA | |
| SCHEMBL9375245 | 0.86 | PPARG (0.60) | MAPTPPARGFFAR1MAOAALDH1A1 | |
| SCHEMBL9570601 | 0.85 | MAOB (0.61) | MAPTPPARGHRH3FFAR1MAOA | |
| SCHEMBL9570600 | 0.84 | MAPT (0.69) | MAPTPPARGHRH3FFAR1MAOA | |
| SCHEMBL9570606 | 0.84 | MAPT (0.69) | MAPTPPARGHRH3FFAR1MAOA | |
| SCHEMBL9371924 | 0.84 | PPARG (0.63) | MAPTPPARGHRH3FFAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533933-A1 | BISHETEROCYCLIC COMPOUND | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |