SCHEMBL9570773

SCHEMBL9570773

Fc1cccc(C(COCc2cccc(Oc3ccccc3)c2)C(F)(F)F)c1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CETP P11597 8/20 0.48
MAN2A1 Q16706 1/20 0.39
MAN1B1 Q9UKM7 1/20 0.39
TACR1 P25103 7/20 0.39
CACNA1F O60840 1/20 0.39
CACNA1D Q01668 1/20 0.39
CACNA1S Q13698 1/20 0.39
CACNA1C Q13936 1/20 0.39
CNR2 P34972 1/20 0.38
MGLL Q99685 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7930457 0.91 CETP (0.45) CETPTACR1CACNA1FCACNA1DCACNA1S
SCHEMBL9570765 0.89 CETP (0.44) CETPMGLL
SCHEMBL9570863 0.87 TACR1 (0.46) CETPTACR1CACNA1FCACNA1DCACNA1S
SCHEMBL9570571 0.87 CETP (0.43) CETPTACR1
SCHEMBL9570885 0.86 TACR1 (0.37) CETPMAN2A1MAN1B1TACR1CACNA1F
SCHEMBL9570718 0.84 CETP (0.40) CETPTACR1MGLL
SCHEMBL9570753 0.83 CETP (0.41) CETPMGLL
SCHEMBL9560487 0.83 PPARG (0.47) CETPTACR1
SCHEMBL9560903 0.83 FFAR1 (0.46) CETPTACR1
SCHEMBL9570872 0.83 CETP (0.48) CETPTACR1CACNA1FCACNA1DCACNA1S

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed