SCHEMBL9570571

SCHEMBL9570571

Cc1cccc(C(COCc2cccc(Oc3ccccc3)c2)C(F)(F)F)c1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CETP P11597 10/20 0.43
TACR1 P25103 7/20 0.41
FFAR1 O14842 1/20 0.40
NPSR1 Q6W5P4 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
GAA P10253 1/20 0.40
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7930457 0.90 CETP (0.45) CETPTACR1FFAR1
SCHEMBL9560903 0.89 FFAR1 (0.46) CETPTACR1FFAR1
SCHEMBL9570773 0.87 CETP (0.48) CETPTACR1
SCHEMBL9570863 0.86 TACR1 (0.46) CETPTACR1
SCHEMBL9570910 0.86 FFAR1 (0.37) TACR1FFAR1NPSR1L3MBTL1GAA
SCHEMBL9560683 0.85 KDM4E (0.50) CETPTACR1FFAR1
SCHEMBL9570794 0.84 FFAR1 (0.44) CETPFFAR1
SCHEMBL9570765 0.83 CETP (0.44) CETPFFAR1
SCHEMBL409247 0.83 FFAR1 (0.51) CETPFFAR1
SCHEMBL9561406 0.83 FFAR1 (0.51) CETPFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed