Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570870 | 0.76 | MAPT (0.34) | MAPTHIF1AEPAS1HTR2AKDM4E | |
| SCHEMBL12035990 | 0.75 | HPGD (0.40) | MAPTHIF1AEPAS1KDM4EALDH1A1 | |
| SCHEMBL9570569 | 0.73 | HDAC3 (0.49) | MAPTKDM4E | |
| SCHEMBL9570760 | 0.73 | TDP1 (0.46) | MAPTHTR2AKDM4EALDH1A1GAA | |
| SCHEMBL9570585 | 0.71 | CYP3A4 (0.47) | MAPTKDM4EALDH1A1 | |
| SCHEMBL10407712 | 0.69 | PKM (0.36) | MAPTHIF1AEPAS1HTR2AKDM4E | |
| SCHEMBL9570582 | 0.69 | KMT2A (0.39) | ESR1ESR2ALDH1A1GAAHSD17B10 | |
| SCHEMBL9570893 | 0.69 | KMT2A (0.36) | ESR1ESR2ALDH1A1GAA | |
| SCHEMBL15724661 | 0.68 | AKR1B1 (0.46) | MAPTHIF1AEPAS1HTR2AAKR1B1 | |
| SCHEMBL5546007 | 0.68 | MAPT (0.60) | MAPTESR1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545891-A2 | Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-06-09 | — | — | EP | disclosed |
| US-4840971-A | INSECTICIDES, MITICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-06-20 | — | — | US | disclosed |