SCHEMBL9570824

SCHEMBL9570824

CCCCCCOC(=O)CCc1ccc(C(=O)O)cc1

nearest known ligand 0.65

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.61
TSHR P16473 1/20 0.61
RARB P10826 9/20 0.60
PLA2G4B P0C869 6/20 0.60
MEN1 O00255 1/20 0.60
ALDH1A1 P00352 1/20 0.60
RARA P10276 1/20 0.60
MAPT P10636 1/20 0.60
MTOR P42345 1/20 0.60
KMT2A Q03164 1/20 0.60
HTT P42858 1/20 0.57
PLA2G4A P47712 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8775319 0.87 RARB (0.59) TP53TSHRRARBPLA2G4BMEN1
SCHEMBL7636074 0.87 TDP1 (0.72) TP53TSHRALDH1A1
SCHEMBL19066804 0.87 TDP1 (0.72) TP53TSHRALDH1A1
SCHEMBL23581130 0.87 TDP1 (0.72) TP53TSHRALDH1A1
SCHEMBL10892112 0.85 ESR1 (0.57) TP53TSHRALDH1A1
SCHEMBL2728741 0.85 ESR1 (0.57) TP53TSHRALDH1A1
Terephthalic Acid SCHEMBL17504571 0.85 TP53 (0.65) TP53TSHRRARBPLA2G4BMAPT
SCHEMBL19920977 0.85 TDP1 (0.74) TP53TSHRALDH1A1
Cetyl Palmitate SCHEMBL8430810 0.82 TSHR (0.60) TP53TSHRRARBPLA2G4BALDH1A1
SCHEMBL11133073 0.82 THRA (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5294896-A None JP disclosed
JP-H05294896-A OPTICALLY ACTIVE AROMATIC GROUP-SUBSTITUTED ALKANOIC ACID ESTER DERIVATIVE AND ITS PRODUCTION HITACHI CHEM CO LTD 1993-11-09 JP disclosed